There were two James Waynes singing blues in 1950s America: a rather prolific James Wayne from Houston, TX, and a less prolific James Wayne from Elizabeth, NJ.
The one from New Jersey recorded a song called 'This Little Letter' for Angeletone in 1960.
There is more information on the one from Texas, who was born James Douglas Waynes, 1924, Houston, TX, United States. A Last.fm user wrote the following biography:
I first heard James Wayne(s) via "Travelin' Mood" on the LP "Urban Blues: New Orleans Bounce" (Imperial LM-94004) .